491 research outputs found
Hyperboloidal slicing approach to quasinormal mode expansions: The Reissner-Nordström case
International audienceWe study quasinormal modes of black holes, with a focus on resonant (or quasinormal mode) expansions, in a geometric frame based on the use of conformal compactifications together with hyperboloidal foliations of spacetime. Specifically, this work extends the previous study of Schwarzschild in this geometric approach to spherically symmetric asymptotically flat black-hole spacetimes, in particular Reissner-Nordström. The discussion involves, first, the nontrivial technical developments needed to address the choice of appropriate hyperboloidal slices in the extended setting as well as the generalization of the algorithm determining the coefficients in the expansion of the solution in terms of the quasinormal modes. In a second stage, we discuss how the adopted framework provides a geometric insight into the origin of regularization factors needed in Leaver’s Cauchy-based foliations, as well as into the discussion of quasinormal modes in the extremal black-hole limit
Three little pieces for computer and relativity
Numerical relativity has made big strides over the last decade. A number of
problems that have plagued the field for years have now been mostly solved.
This progress has transformed numerical relativity into a powerful tool to
explore fundamental problems in physics and astrophysics, and I present here
three representative examples. These "three little pieces" reflect a personal
choice and describe work that I am particularly familiar with. However, many
more examples could be made.Comment: 42 pages, 11 figures. Plenary talk at "Relativity and Gravitation:
100 Years after Einstein in Prague", June 25 - 29, 2012, Prague, Czech
Republic. To appear in the Proceedings (Edition Open Access). Collects
results appeared in journal articles [72,73, 122-124
Mass and Angular Momentum in General Relativity
We present an introduction to mass and angular momentum in General
Relativity. After briefly reviewing energy-momentum for matter fields, first in
the flat Minkowski case (Special Relativity) and then in curved spacetimes with
or without symmetries, we focus on the discussion of energy-momentum for the
gravitational field. We illustrate the difficulties rooted in the Equivalence
Principle for defining a local energy-momentum density for the gravitational
field. This leads to the understanding of gravitational energy-momentum and
angular momentum as non-local observables that make sense, at best, for
extended domains of spacetime. After introducing Komar quantities associated
with spacetime symmetries, it is shown how total energy-momentum can be
unambiguously defined for isolated systems, providing fundamental tests for the
internal consistency of General Relativity as well as setting the conceptual
basis for the understanding of energy loss by gravitational radiation. Finally,
several attempts to formulate quasi-local notions of mass and angular momentum
associated with extended but finite spacetime domains are presented, together
with some illustrations of the relations between total and quasi-local
quantities in the particular context of black hole spacetimes. This article is
not intended to be a rigorous and exhaustive review of the subject, but rather
an invitation to the topic for non-experts. In this sense we follow essentially
the expositions in Szabados 2004, Gourgoulhon 2007, Poisson 2004 and Wald 84,
and refer the reader interested in further developments to the existing
literature, in particular to the excellent and comprehensive review by Szabados
(2004).Comment: 41 pages. Notes based on the lecture given at the C.N.R.S. "School on
Mass" (June 2008) in Orleans, France. To appear as proceedings in the book
"Mass and Motion in General Relativity", eds. L. Blanchet, A. Spallicci and
B. Whiting. Some comments and references added
Sublittoral soft bottom communities and diversity of Mejillones Bay in northern Chile (Humboldt Current upwelling system)
The macrozoobenthos of Mejillones Bay (23°S; Humboldt Current) was quantitatively investigated over a 7-year period from austral summer 1995/1996 to winter 2002. About 78 van Veen grab samples taken at six stations (5, 10, 20 m depth) provided the basis for the analysis of the distribution of 60 species and 28 families of benthic invertebrates, as well as of their abundance and biomass. Mean abundance (2,119 individuals m-2) was in the same order compared to a previous investigation; mean biomass (966 g formalin wet mass m-2), however, exceeded prior estimations mainly due to the dominance of the bivalve Aulacomya ater. About 43% of the taxa inhabited the complete depth range. Mean taxonomic Shannon diversity (H', Log e) was 1.54 ± 0.58 with a maximum at 20 m (1.95 ± 0.33); evenness increased with depth. The fauna was numerically dominated by carnivorous gastropods, polychaetes and crustaceans (48%). About 15% of the species were suspensivorous, 13% sedimentivorous, 11% detritivorous, 7% omnivorous and 6% herbivorous. Cluster analyses showed a significant difference between the shallow and the deeper stations. Gammarid amphipods and the polychaete family Nephtyidae characterized the 5-mzone, the molluscs Aulacomya ater, Mitrella unifasciata and gammarids the intermediate zone, while the gastropod Nassarius gayi and the polychaete family Nereidae were most prominent at the deeper stations. The communities of the three depth zones did not appear to be limited by hypoxia during non-El Niño conditions. Therefore, no typical change in community structure occurred during El Niño 1997–1998, in contrast to what was observed for deeper faunal assemblages and hypoxic bays elsewhere in the coastal Humboldt Current system
Motion in classical field theories and the foundations of the self-force problem
This article serves as a pedagogical introduction to the problem of motion in
classical field theories. The primary focus is on self-interaction: How does an
object's own field affect its motion? General laws governing the self-force and
self-torque are derived using simple, non-perturbative arguments. The relevant
concepts are developed gradually by considering motion in a series of
increasingly complicated theories. Newtonian gravity is discussed first, then
Klein-Gordon theory, electromagnetism, and finally general relativity. Linear
and angular momenta as well as centers of mass are defined in each of these
cases. Multipole expansions for the force and torque are then derived to all
orders for arbitrarily self-interacting extended objects. These expansions are
found to be structurally identical to the laws of motion satisfied by extended
test bodies, except that all relevant fields are replaced by effective versions
which exclude the self-fields in a particular sense. Regularization methods
traditionally associated with self-interacting point particles arise as
straightforward perturbative limits of these (more fundamental) results.
Additionally, generic mechanisms are discussed which dynamically shift ---
i.e., renormalize --- the apparent multipole moments associated with
self-interacting extended bodies. Although this is primarily a synthesis of
earlier work, several new results and interpretations are included as well.Comment: 68 pages, 1 figur
Profound Chemopreventative Effects of a Hydrogen Sulfide-Releasing NSAID in the APC(Min/+) Mouse Model of Intestinal Tumorigenesis
Canadian Institutes of Health Research grant to JL
Community peer-led falls prevention presentations: What do the experts suggest?
Falls among older adults are a major problem. Despite considerable progress in falls prevention research, older adults often show low motivation to engage in recommended preventive strategies. Peer-led falls prevention education for older adults may have potential for bridging the research evidence-practice gap, thereby promoting the uptake of falls prevention strategies. We evaluated peer educators’ presentations of falls prevention education to community-dwelling older adults in regard to established criteria that were consistent with adult learning principles, the framework of health behaviour change, falls prevention guidelines, and recommendations for providing falls prevention information. We conducted a within-stage mixed model study using purposive and snowball sampling techniques to recruit 10 experts to evaluate video recordings of the delivery of three peer-led falls prevention presentations. Each expert viewed three videos and rated them using a questionnaire containing both open-ended and closed items. There was a good level of expert agreement across the questionnaire domains. Though the experts rated some aspects of the presentations highly, they thought that the presentations were mainly didactic in delivery, not consistently personally relevant to the older adult audience, and did not encourage older adults to engage in the preventive strategies that were presented. Based on the experts’ findings, we developed five key themes and recommendations for the effective delivery of peer led falls prevention presentations. These included recommending that peer educators share falls prevention messages in a more interactive and experiential manner and that uptake of strategies should be facilitated by encouraging the older adults to develop a personalised action plan. Findings suggest that if peer-led falls prevention presentations capitalise on older adults’ capability, opportunity, and motivation, the older adults may be more receptive to take up falls prevention messages
Double blind, randomized, placebo controlled clinical trial for the treatment of diabetic foot ulcers, using a nitric oxide releasing patch: PATHON
<p>Abstract</p> <p>Background</p> <p>Diabetes Mellitus constitutes one of the most important public health problems due to its high prevalence and enormous social and economic consequences. Diabetic foot ulcers are one of the chronic complications of diabetes mellitus and constitute the most important cause of non-traumatic amputation of inferior limbs. It is estimated that 15% of the diabetic population will develop an ulcer sometime in their lives. Although novel therapies have been proposed, there is no effective treatment for this pathology. Naturally produced nitric oxide participates in the wound healing process by stimulating the synthesis of collagen, triggering the release of chemotactic cytokines, increasing blood vessels permeability, promoting angiogenic activity, stimulating the release of epidermical growth factors, and by interfering with the bacterial mitochondrial respiratory chain. Topically administered nitric oxide has demonstrated to be effective and safe for the treatment of chronic ulcers secondary to cutaneous leishmaniasis. However, due to their unstable nitric oxide release, the topical donors needed to be applied frequently, diminishing the adherence to the treatment. This difficulty has led to the development of a multilayer polymeric transdermal patch produced by electrospinning technique that guarantees a constant nitric oxide release. The main objective of this study is to evaluate the effectiveness and safety of this novel nitric oxide releasing wound dressing for the treatment of diabetic foot ulcers.</p> <p>Methods and design</p> <p>A double-blind, placebo-controlled clinical trial, including 100 diabetic patients was designed. At the time of enrollment, a complete medical evaluation and laboratory tests will be performed, and those patients who meet the inclusion criteria randomly assigned to one of two groups. Over the course of 90 days group 1 will receive active patches and group 2 placebo patches. The patients will be seen by the research group at least every two weeks until the healing of the ulcer or the end of the treatment. During each visit the healing process of the ulcer, the patient's health status and the presence of adverse events will be assessed. Should the effectiveness of the patches be demonstrated an alternative treatment would then be available to patients.</p> <p>Trial registration</p> <p>NCT00428727.</p
Historical Isolation versus Recent Long-Distance Connections between Europe and Africa in Bifid Toadflaxes (Linaria sect. Versicolores)
Background: Due to its complex, dynamic and well-known paleogeography, the Mediterranean region provides an ideal framework to study the colonization history of plant lineages. The genus Linaria has its diversity centre in the Mediterranean region, both in Europe and Africa. The last land connection between both continental plates occurred during the Messinian Salinity Crisis, in the late Miocene (5.96 to 5.33 Ma). Methodology/Principal Findings: We analyzed the colonization history of Linaria sect. Versicolores (bifid toadflaxes), which includes c. 22 species distributed across the Mediterranean, including Europe and Africa. Two cpDNA regions (rpl32-trnL UAG and trnK-matK) were sequenced from 66 samples of Linaria. We conducted phylogenetic, dating, biogeographic and phylogeographic analyses to reconstruct colonization patterns in space and time. Four major clades were found: two of them exclusively contain Iberian samples, while the other two include northern African samples together with some European samples. The bifid toadflaxes have been split in African and European clades since the late Miocene, and most lineage and speciation differentiation occurred during the Pliocene and Quaternary. We have strongly inferred four events of post-Messinian colonization following long-distance dispersal from northern Africa to the Iberian Peninsula, Sicily and Greece. Conclusions/Significance: The current distribution of Linaria sect. Versicolores lineages is explained by both ancien
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